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An undescended testicle, sometimes called a cryptorchid testicle, is a fairly common problem in male babies. Typically, testicles undescended at birth will move into the scrotum within the first year of life, however in a small percentage of cases, this migration does not occur.
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The invention further relates to diagnostic and therapeutic methods useful for diagnosing, treating, preventing and/or prognosing disorders related to the testes, including testicular cancer, and therapeutic methods for treating such disorders. The invention further relates to screening methods for identifying agonists and antagonists of polynucleotides.
M). Field ofthe Invention 003 The present invention relates to novel testes related polynucleotides, the polypeptides encoded by these polynucleotides herein collectively referred to as "testicular antigens and antibodies that immunospecifically bind these polypeptides, and the use of such testicular polynucleotides, antigens, and antibodies for.
Nucleic Acids, Proteins, and Antibodies 001 This application refers to a "Sequence Listing" that is provided only on electronic media in computer readable form pursuant to Administrative Instructions Section 801(a i). The Sequence Listing forms a part of this description pursuant to Rule 5.2 and.
010 Thus, the discovery of new human testicular associated polynucleotides, the polypeptides encoded by them, and antibodies that immunospecifically bind these polypeptides, satisfies a need in the art by providing new compositions which are useful in the diagnosis, treatment, prevention and/or prognosis of disorders of.
Specifically, erectile function is impaired, as well as libido and sperm production. 005 Known dysfimctions of sperm production include aspermia (the failure to produce an ejaculate asthenospermia (the production of an ejaculate in which less than 50 of spermatozoa are motile azoospermia (the production of.
Но кончается детство - и все его уроки забыты. Люди показались бы себе тогда маленькими и беззащитными, несмотря на всеобщее благо и согласие.
The invention further relates to methods and/or compositions for inhibiting or promoting the production and/or function ofthe polypeptides ofthe invention. Detailed Description Tables 012 Table IA summarizes some of the polynucleotides encompassed by the invention (including cDNA clones related to the sequences (Clone ID NO:Z.